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Brings together functional and structural informationrelevant to the design of drugs targeting zinc enzymes The second most abundant transition element in living organisms, zinc spans all areas of metabolism, with zinc-containing proteins offering both established and...
Editeur :
Wiley
Parution :
2009-10-22
Collection :
Wiley Series in Drug Discovery and Development
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A consolidated and comprehensive reference on ligand-binding assays Ligand-binding assays (LBAs) stand as the cornerstone of support for definition of the pharmaco-kinetics and toxicokinetics of macromolecules, an area of burgeoning interest in the pharmaceutical...
Editeur :
Wiley
Parution :
2009-10-22
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Stimulation of the immune system’s ability to control and destroy tumors cont- ues to be the goal of cancer immune therapy; but the scope has rapidly expanded; approaches are constantly updated; new molecules are continually introduced; and immune mechanisms are...
Editeur :
Springer
Parution :
2009-10-09
ePub
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I have always been interested in chemistry and biology. My undergraduate, graduate, and postdoctoral trainings in pharmacy, medicinal chemistry and pharmacology, respectively, have strengthened this interest and led me to realize that significant advances in medicine...
Editeur :
Springer
Parution :
2009-10-08
ePub
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To describe principles of optical imaging including chemistry and physics of fluorescence, limitations/advantages of optical imaging compared to metabolic and anatomic imaging.
Describe hardware adapted for small animal imaging and for clinical applications: endoscopes...
Editeur :
Springer
Parution :
2009-10-03
ePub
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Drug Bioavailability In order to reach its intended site of action, the drug molecules in every pill that we swallow must first be absorbed, transported via the bloodstream and evade various mechanisms that eliminate drugs from the body. Those drug properties that...
Editeur :
Wiley-VCH
Parution :
2009-09-18
Collection :
Methods & Principles in Medicinal Chemistry
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My journey into this fascinating field of biotechnology started about 26 years ago at a small biotechnology company in South San Francisco called Genentech. I was very fortunate to work for the company that begat the biotech industry during its formative years. This...
Editeur :
Springer
Parution :
2009-09-18
ePub
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The Novartis Foundation Series is a popular collection of the proceedings from Novartis Foundation Symposia, in which groups of leading scientists from a range of topics across biology, chemistry and medicine assembled to present papers and discuss results.The Novartis...
Editeur :
Wiley
Parution :
2009-09-16
Collection :
Novartis Foundation Symposia
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The Novartis Foundation Series is a popular collection of the proceedings from Novartis Foundation Symposia, in which groups of leading scientists from a range of topics across biology, chemistry and medicine assembled to present papers and discuss results.The Novartis...
Editeur :
Wiley
Parution :
2009-09-16
Collection :
Novartis Foundation Symposia
PDF
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The Novartis Foundation Series is a popular collection of the proceedings from Novartis Foundation Symposia, in which groups of leading scientists from a range of topics across biology, chemistry and medicine assembled to present papers and discuss results.The Novartis...
Editeur :
Wiley
Parution :
2009-09-16
Collection :
Novartis Foundation Symposia
PDF
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A unique reference on peripheral pain receptor mechanisms While considerable advances have been made on pharmacotherapies for many chronic disease states, options available to treat chronic pain have remained relatively unchanged for decades. However, utilizing the...
Editeur :
Wiley
Parution :
2009-09-01
PDF
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Chronopharmaceutics Science and Technology for Biological Rhythm Guided Therapy and Prevention of Diseases Edited by Bi-Botti C. Youan The first standard reference on chronopharmaceutics As we better understand how biological processes unfold in real time through...
Editeur :
Wiley
Parution :
2009-08-26
PDF
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Cancers of the central nervous system are among the most lethal of human neoplasms. They are recalcitrant to even intensive multimodality therapies that include surgery, radiotherapy, and chemotherapy. Moreover, especially in children, the consequences of these...
Editeur :
Humana
Parution :
2009-08-15
ePub
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Covers powerful new tools for drug development Molecular pathology offers tools and techniques that can greatly enhance the drug discovery and development process, helping to make the promises of personalized medicine a reality. Molecular Pathology in Drug Discovery and...
Editeur :
Wiley
Parution :
2009-08-06
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Benefit-risk assessment is at the centre of the approval process for every new medicine. The ability to assess the risks of a new medicine accurately and to balance these against the benefits the medicine could bring is critical for every regulatory authority and...
Editeur :
Wiley
Parution :
2009-08-04
PDF
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Barrier, reservoir, target site - those are but some of the possible functions of biological lipid membranes in the complex interplay of drugs with the organism. A detailed knowledge of lipid membranes and of the various modes of drug-membrane interaction is therefore...
Editeur :
Wiley-VCH
Parution :
2009-07-10
Collection :
Methods & Principles in Medicinal Chemistry
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A comprehensive review of the most current scientific research on ABC transporters and multidrug resistance ATP-binding cassette transporter genes (ABC transporters) are known to play a crucial role in the development of multidrug resistance (MDR). MDR is the ability...
Editeur :
Wiley
Parution :
2009-06-17
Collection :
Wiley Series in Drug Discovery and Development
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It was estimated that in 2008, 1,437,180 patients would receive a new cancer diagnosisand 565,650individualswould die of cancer (Jemal et al. 2008).Since the vast majority of patients dying of cancer will have had anticancer therapy, both c- ventional chemotherapy and...
Editeur :
Springer
Parution :
2009-06-12
ePub
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