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Mercury (Hg) is a global pollutant that knows no environmental boundaries. Even the most stringent control of anthropogenic Hg sources will not eliminate exposure given its ubiquitous presence. Exposure to Hg occurs primarily via the food chain due to MeHg’s...
Editeur :
Springer
Parution :
2012-03-23
ePub
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This book answers the questions about the process and costs of pharmaceutical R & D in a compelling narrative focused on the discovery and development of important new medicines. It gives an insider's account of the pharmaceutical industry drug discovery process, the...
Editeur :
Wiley
Parution :
2012-03-02
PDF, ePub
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This book provides a comprehensive look at renal cell carcinoma, exploring its biology as well as current and future molecular targets for renal cancer carcinoma.
Editeur :
Springer
Parution :
2012-02-28
ePub
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The obesity pandemic continues to increase on a world-wide basis with over 70% of the United States population being either overweight or obese. Hematologic malignancies have recently been identified among the obesity associated malignancies spanning the lifespan from...
Editeur :
Springer
Parution :
2012-02-25
ePub
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The only book dedicated to physiologically-based pharmacokinetic modeling in pharmaceutical science Physiologically-based pharmacokinetic (PBPK) modeling has become increasingly widespread within the pharmaceutical industry over the last decade, but without one...
Editeur :
Wiley
Parution :
2012-02-17
PDF, ePub
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Recently the CXCR4/CXCL12-axis has been recognized as one of the pivotal adhesion pathways by which hematopoietic stem cells are retained in the bone marrow. CXCR4 antagonists with different chemical specification are being developed. Pharmacology research guides the...
Editeur :
Springer
Parution :
2012-02-15
ePub
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Practical Utility of Biomarkers in Drug Discovery and Development covers all aspects of biomarker research applied to drug discovery and development and contains state-of-the-art appraisals on the practical utility of genomic, biochemical, and protein biomarkers. Case...
Editeur :
Wiley
Parution :
2012-02-14
Collection :
Wiley Series on Technologies for the Pharmaceutical Industry
PDF, ePub
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The acknowledgment that viruses are potent biological factors in driving many cancers have seen a dramatic upsurge in recent years in large part to the success of the human papilloma virus vaccine against invasive cervical carcinomas and followed by the awarding of the...
Editeur :
Springer
Parution :
2012-02-14
Collection :
Current Cancer Research
ePub
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This book fulfils an urgent need for an updated text on pediatric psychopharmacology. It takes a unique approach in discussing recent findings within the context of current issues, including economic and political ones. The book covers the emerging question of treating...
Editeur :
Wiley-Blackwell
Parution :
2012-02-10
PDF, ePub
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In May of 2011, Western Europe experienced a severe outbreak of Shiga toxin (Stx)-producing E. coli (STEC) that culminated in more than 3200 cases and 39 deaths. While Stx is not the only virulence factor associated with STEC, it is certainly the primary determinant...
Editeur :
Springer
Parution :
2012-02-10
Collection :
Current Topics in Microbiology and Immunology
ePub
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This is a comprehensive source of information on the application of ion chromatography (IC) in the analysis of pharmaceutical drugs and biologicals.This book, with contributors from academia, pharma, the biotech industry, and instrument manufacturing, presents the...
Editeur :
Wiley
Parution :
2012-02-07
PDF, ePub
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An essential outline of the main facets of polypharmacology in drug discovery research Extending drug discovery opportunities beyond the "one drug, one target" philosophy, a polypharmacological approach to the treatment of complex diseases is emerging as a hot topic in...
Editeur :
Wiley
Parution :
2012-01-20
PDF, ePub
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Microneedles can be used for delivery of a wide range of drug substances for practically any medical condition and present a real opportunity for vaccines and medicines that are unsuitable for oral administration or conventional patch delivery. Microneedle-mediated...
Editeur :
Wiley-Blackwell
Parution :
2012-01-17
PDF, ePub
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This volume is focused on the development of vaccines which generate immune effectors capable of blocking mucosal entry or peripheral pathogen spread. A critical first step in the design of mucosal vaccines is the selection of administration route. Not all mucosal...
Editeur :
Springer
Parution :
2012-01-10
Collection :
Current Topics in Microbiology and Immunology
ePub
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Pharmacogenomics is the basis of personalized medicine which will be the medicine of the future. Through both reducing the numbers of adverse drug reactions and improving the use of existing drugs in targeted populations, pharmacogenomics represents a real advance on...
Editeur :
Wiley-Blackwell
Parution :
2012-01-09
PDF, ePub
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This book explains the importance and practice of pediatric drug testing for pharmaceutical and toxicology professionals. It describes the practical and ethical issues regarding non-clinical testing to meet US FDA Guidelines, differences resulting from the new European...
Editeur :
Wiley
Parution :
2011-12-28
PDF, ePub
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This book describes how to address the analysis of aggregates and particles in protein pharmaceuticals, provides a comprehensive overview of current methods and integrated approaches used to quantify and characterize aggregates and particles, and discusses regulatory...
Editeur :
Wiley
Parution :
2011-12-20
PDF, ePub
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Practical drug development approaches presented by leading experts Designed to support the development of new, effective therapeutics, Topical and Transdermal Drug Delivery: Principles and Practice explains the principles underlying the field and then demonstrates how...
Editeur :
Wiley
Parution :
2011-12-15
PDF, ePub
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This book provides an overview of critical components of cell signaling machinery and its role in epithelial morphogenesis, proliferation, invasions and angiogenesis in human cancer and discusses novel types of protein kinase pathways.
Editeur :
Springer
Parution :
2011-12-02
ePub
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Lecture Notes: Clinical Pharmacology and Therapeutics provides all the necessary information, within one short volume, to achieve a thorough understanding of how drugs work, their interaction with the body in health and disease, and how to use these drugs appropriately...
Editeur :
Wiley-Blackwell
Parution :
2011-11-28
Collection :
Lecture Notes
ePub
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